Certified Tumor Registrar (CTR) Practice Exam

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Where are the islets of Langerhans located in the human body?

Liver
Pancreas
Kidneys
Heart

The correct answer is: Pancreas

The islets of Langerhans are clusters of cells found within the pancreas. They play a crucial role in the endocrine system, specifically in the regulation of glucose metabolism. These islets contain different types of cells, including alpha cells that produce glucagon and beta cells that produce insulin, both of which are vital for maintaining blood sugar levels. The pancreas itself is positioned behind the stomach and is involved not only in digestive functions through its exocrine cells but also in hormone production through the islets of Langerhans. This dual role highlights the importance of the pancreas in overall metabolic health, making it clear why the islets are specifically located in this organ. The other options listed—liver, kidneys, and heart—do not contain islets of Langerhans and serve different physiological functions. Understanding where these structures are located helps in recognizing their function and significance in diseases such as diabetes, where insulin regulation is impaired.