Certified Tumor Registrar (CTR) Practice Exam

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What type of agent is Methotrexate classified as?

Antibiotic
Chemotherapy
Antiviral
Immunotherapy

The correct answer is: Chemotherapy

Methotrexate is classified as a chemotherapy agent. It works by inhibiting the metabolism of folic acid, which is necessary for the synthesis of nucleotides and ultimately DNA. This action makes it effective in treating various types of cancer, as it hinders the proliferation of rapidly dividing cancer cells. In addition to its cancer treatment applications, Methotrexate is also used in lower doses for autoimmune conditions such as rheumatoid arthritis and psoriasis, but its primary classification in the context of cancer treatment marks it as a chemotherapy drug. Understanding the classification of Methotrexate is crucial for tumor registrars as it helps in comprehending treatment regimens and their implications for patient management and data abstraction within cancer registries.