Certified Tumor Registrar (CTR) Practice Exam

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The presence of Reed-Sternberg cells is indicative of which type of disease?

  1. Non-Hodgkin's lymphoma

  2. Hodgkin's disease

  3. Leukemia

  4. Liver cancer

The correct answer is: Hodgkin's disease

The presence of Reed-Sternberg cells is a hallmark characteristic of Hodgkin's disease, also known as Hodgkin lymphoma. These cells are large, abnormal lymphocytes that can be identified through specific staining techniques in a tissue sample, typically from a lymph node biopsy. The discovery of these distinct cells is crucial for the diagnosis of Hodgkin lymphoma and differentiates it from other types of lymphomas, including Non-Hodgkin's lymphoma, which does not include Reed-Sternberg cells. This differentiation is important in clinical practice because Hodgkin lymphoma has a distinct treatment approach and prognosis compared to Non-Hodgkin's lymphoma and other malignancies such as leukemia or liver cancer. Identifying Reed-Sternberg cells provides essential information regarding the etiology and classification of the disease, guiding appropriate management and therapeutic strategies.

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